Friday, September 6, 2019
Marketing Techniques Essay Example for Free
Marketing Techniques Essay The main thing behind marketing in a business is finding the customerââ¬â¢s needs and produce the product/ services to satisfy their needs, this way the customer can choose what they would want included in their product/ service. A business that follows this rule is market-orientated. There is alternatives orientation for businesses, these are; The production concept: This is where the business produces in large quantities and distribute in bulk, this is so the customer/ business get the products cheaper as they will be bulk buying. A business that would do this is Walkers. They make thousands of packets and then sells them to large business such as Tesco, Tesco would be able to buy it for cheaper as they will be buying in a very large amount as they can stock allot of products. However charity shops will sell their products and with the entire surplus they send it off to the charity. An example of this is Oxfam, they will sell their products to the public and with all the surplus is sent off to the project they are currently on. The sales concept: Businesses need to know how to sell their products/ services. If they donââ¬â¢t know how to the business is likely to fail but if a business knows how to sell its goods/ sieves then it is likely to be successful. A type of sales technique is hard selling nor Tesco or Oxfam hard sell but businesses such as Anglian, Everest and Safestyle are usually hard sellers trying to get you to buy double glazing. As you can see some of the sales reps in these businesses have lied about the business just so they can close sales with people on the spot. The marketing Concept: Marketing concept is different to sales and production as it has to take every step with keeping customers in mind as marketing is based around customerââ¬â¢s needs and wishes. An example for this is Tesco they do this with their Tesco Club card every time you shop you swipe your card and the system knows what the customer purchased, so to bring back the customer they will mail you some vouchers which then makes the customer want to come back into the store and shop again. Another business that uses marketing is Curryââ¬â¢s when you purchase something the sales assistant take down your home address so if they have any offers which are similar to what you bought will send you letter informing you about any offers. Marketing definitions: Basic definition of marketing is meeting customer needs and wants profitably. Marketing consists of identifying, anticipating and satisfying customer requirements profitably. Objectives: Private sector The objectives for a private sector business are to maximise profits and expand all over the world. An example for a private sector business is Tesco. They have businesses in the UK and in America called Fresh Easy. In the screen shot you can see Tescoââ¬â¢s objectives. Public sector The objectives for a public sector business are to provide quality service for the public. An example for this is the NHS as they provide health care for everyone. In the screenshot you can see NHSââ¬â¢s objectives. Voluntary sector The voluntary sector businesses objectives are to raise money for good causes. An example of this is Oxfam they aid anyone to donate any goods so they can sell them and send the money they produce from the goods they sell given to the public to projects they are currently on. As you can see this is one of Oxfamââ¬â¢s shops where they sell goods that have been donated by the public. Organisational objective This is a target for the whole business no matter how big it is. A good example of this is Tesco, Tescoââ¬â¢s objective may be to increase market share to 51%. Marketing objective This is how you are going to achieve it e.g. increase Tesco value products Tesco can produce their own products such as Ben Jerry ice-cream they can produce a Tesco value version as some people may not be able to afford à £4 ice-cream so the people can buy the alternative which would help Tesco increase their profits. Link between organisational objectives and marketing objectives Marketing objectives shouldnââ¬â¢t be contradicting a businessââ¬â¢s main objective, but should be contributing in achieving that. A business will not succeed if itââ¬â¢s been pulled apart in two different directions. An example of this is if Tesco want to increase their sales by a certain percentage then different functional areas have to contribute to achieve this such as advertising they may advertise products that are on offer or any seasonal products e.g. Christmas, new years or valentines. Tescoââ¬â¢s could also send out more offers with their Club Card meaning more customers may shop in the business. By this way Tesco will be informing a lot more people that they have sales on which might bring more customers into the business. Market leadership This is where a business has the most market share in a given product or service, this could be measured by the amount of goods sold or the value of those goods. If a business wants to become a market leader they need to be 51% or more in sales for it to become a market leader. For example, Tesco is the leading supermarket in the supermarket market place as you can see in this screenshot (January 2012). Charity do no compete with market share as they all have similar aims and objectives but need maximum funds to stay in operation. Some charities will be more valuable then others depending on how much donations they receive. Oxfam is at the top along with cancer research UK, British Heart Foundation and many more. Brand awareness Brand awareness is making people aware of the business and what they do/ sell. Brand awareness is the NHSââ¬â¢s number one objective, they want all of Great Britainââ¬â¢s public to know what they do. Brand awareness may be an individual product or the whole business itself. Tesco may advertise their Tesco club card so people are more aware of the club card you can get when you sign up with them. Perceptions of customers A customerââ¬â¢s perception of a business or a brand often affects their purchasing decision. An example of this is a business might have a lot of brand awareness but their products might not be of the highest quality. This will make the customer not want to come back into the store as they are paying for a cheap quality product. Tesco has a reputation of selling goods a cheap price to everyone, if they start selling their products higher than their competitors then they are likely to lose out on customers and sales which are why they try keep their prices as low as possible. People may also decide to shop at Oxfam for clothes rather than buying clothes from the high street as they know their money goes to good use. Techniques: Growth strategies Businesses grow through their products/ services every time they put a product on the market more and more people will find out about the product. For example Tesco have been using growth strategies as they are expanding with their services, such as Tesco Money, you can now have a credit card with Tesco which people who may donââ¬â¢t normally do not shop at Tesco may have their Tesco credit card. Oxfam use growth strategies through advertising. Every time they advertise someone new will hear about Oxfam and how they are helping to take people out of poverty in third world countries. Survival strategies This is important for all business if they want to keep operating. The reason why Tesco are expanding into different markets is in case one market fails them they have other services which will help them keep out of making a loss for example if Tesco started making cars and sold a few thousand but then was not successful. They are likely to start making a loss but as they are successful in other markets they are unlikely that they would shut down. With Oxfam with all their stores open they can use them stores to survive. Branding Business need to have a strong brand image in order for them to survive. Providing high customer service will increase the brand image. Advertising is also a factor to increase the brand image. Tesco and Oxfam both have a very strong brand image as they are at the top of their tables Tesco is globally a very well known business and Oxfam is also globally well know as they operate in the UK and in third world countries. Relationship marketing Building a relationship with customers is very important for the business as they will think that the business cares about them. Tesco can build relationships with its customers at the tills, the cashier can communicate with the customer building a positive relationship. This is also the same with Oxfam when people buy products from the stores they are building a relationship with the business or if you support Oxfam through direct debit you will receive a welcome pack with updates every month about what the persons many is doing and how they are helping people in poverty.
Thursday, September 5, 2019
Nightmare Before Christmas | Analysis
Nightmare Before Christmas | Analysis Tim Burton rings in my ears as one of Hollywoods most eccentric directors. There is a distinct and unique phenomenon in his films: the genre of his most films are between animation films and real person films; his animation films overturn the world of traditional fairy tales, showing the darkness of horror, but did not give us the feel of fear. Nightmare before Christmas, which reflects his typical paradigm, is a fantasy mixed of horror, magic, darkness, holidays, the jolly guys, and an interesting skeleton. The features of Nightmare before Christmas have a similarity with Bakhtins theory of carnivalesque. In Bakhtins view, everyone lives a carnivalistic life as long as those carnival laws. His feel of carnival is full of grotesque realism, which can get rid of the horrable things in the world. And the grotesque style can also turn the world into a bright and cheerful one. (Bakhtin,1989). There is always a feel of carnival surrounded in Nightmare before Christmas. Because of the feel, audience can get away from the fear successfully. On the other hand, Bakhtin believes that carnivalistic life is a life drawing out of its usual rut; it is to some extent life turned inside out, the reverse side of the world.( Bakhtin,1989) Similarly, Burton sets two worlds to make a comparision: the human world and underground world; the grotesque world of Halloween and the happy world of Christmas. The confrontation of the two worlds represents Burtons inclination. The happy world is boring while the eerie wolrd is vivid and interesting. In my Nightmare before Christmas lingers on the edge of conventional culture and popular culture, it challenges the conventional culture and queries on the popular culture. So Burton makes an utmost effort to prove the rationality of his subversion in this film. It takes delight in talking about Burtons Gothic darkness of horror. The story happens in the world of ghosts and monsters where we are totally un familiar. The vampire bats, red eye demon , black monsters and even the wretched green, these gothic images are everywhere in the film. They stand in stark contrast to the simplicity of traditional animation films. However, the audience feel more closer to them and come to realize their subsistence status trenchantly. The American animation films have a heroism complex, but Burton deconstructs our expectation of the traditional hero. In Nightmare before Christmas, the character Jack is frightful and he has no mission to save the world. Other character is treated equally, eg. the pet comes along with Jack is soul of a dog instead of a brilliant white horse. More importantly, Burton wants to create a balance between creepy and interesting. So he gives life to the grotesquery Jack who actually is virtuous. He demonstrates the characters individual emotions and action which has no relationship with hero. Specificly, the modeling of Jacks eyes are just two black holes which thoroughly give expression to the meaning of the character. Lets turn to the other film: No Country for Old Men In this film No Country for Old Men the genre pushes the envelope of sanity. It is an unconventional western film, mixed with action, crime drama and dark humor. The McCarthys novel No Country for Old Men is an ideal vehicle for the Coen brothers, who have used violence and emptiness laced with dark humor as an artistic aesthetic in their directing careers. The films greatest achievement is its ability to transport the audience into a world where the predestination, death, fears, choices, morals and realities of life are strikingly brought to life and make the audience reflect upon and look back with careful consideration after the whole experience. The violence and bleakness of it all is not to simply evoke reaction or engage the audience, it is to tell a story and impart an experience of great intention, to which the Coens have brilliantly succeeded. To some extent, this film is a character study of Sheriff Bell, an honest lawman who is wise, observant, grounded in reality, and has a long memory. No Country for Old Men is really his story. And also, The Coen brothers direction of the particularly intense chase scenes between Chigurgh and Moss are masterful, evoking emotions of suspense to the highest level and pushing the audience to the very edge of their seats. At the same time the movie is a character study on the effects of evil and innocence lost, an exploration on the themes of fate and chance, an analysis of the freedom to choose and its consequences, a reflection on evil and good as forces of society and the investigation of basic human emotions such as hope, fear, love, violence and aspiration in the face of a variety of situations. The ending of the film is about death. Faced with the overwhelming fact of death, all of us humans find meaning only by making up their own spiritual codes. The murderers code, the good old boys code, the sheriffs code, the wifes codethey are all equally meaningless, equally inadequate in the face of death, but they are all perfectly legitimate responses to the fact of universal death. The film is also about predestination and free will, Chigurgh doesnt believe in free will, I got here the same way the coin did , he is almost like a robot , and scientifically he is totally right we dont have free will , Chigurgh is not guilty , he just has killer genes and his mother didnt hug him so thats why he turned out to be this way, there are no choices in matter , just cause and effect , only quantum psychics can show some difference. In conclusion, Film genres can take culture as very important elements into consideration. And also, we can characterize a culture by its genre set. Obviously through the film review, we can see that genre can function as a tool to define and describe a culture. Heroes and Villains: Historical Analysis Heroes and Villains: Historical Analysis Heroes, Villains or Both? Austin Rappel What I found most interesting in this weeks readings was the myths behind the men; specifically Ulysses S. Grant, general in chief of the United States Army, William T. Sherman, general in The United States Army and Abraham Lincoln, president of the United States. Grant was considered a drunk, Whatever happened, the story of his drinking became a staple of gossip in the old army. (McPherson, pg.114) Sherman was considered crazy; But Sherman could never entirely escape the reputation of madness (McPherson, pg 114) Lincoln was considered passive: a basic trait of character evident throughout Lincolns life: the essential passivity of his nature. (McPherson, pg. 206) I think it is important to determine if these things were true or if there is enough evidence to ever know for sure the mindset or character of the men that are known to us as the men that defined and ultimately were the victors of the Civil War. Grant quickly rose through the ranks during the Civil War; command of a brigade, a division, an army (Army of Tennessee), an army group, an all of the armies of the United States. (McPherson, pg 110) These accomplishments are a big contrast to what one could consider could be an accomplished by a drunkard. Brooks Simpson , a biographer concluded, Although Grant sometimes took a drink during the war, and may on occasion have taken two, his colleagues who knew him best and were in the best position to observe him were unanimous in their testimony that he was rarely if ever drunk. (McPherson, pg. 114) Grant was also given the reputation as a butcher when the general most deserving of the title was Robert E. Lee. (McPherson, pg 113) Sherman is best known for his March to the Sea; a march of over 700 miles, in which psychological warfare was used in order to stop the war. As stated in McPherson, The terror that his soldiers provoked among Southern whites was a power, he wrote, and I intended to utilize it to humble their pride, to follow them to their inmost recesses, and to make them fear and dread usà ¢Ã¢â ¬Ã ¦ We cannot change the hearts and minds of those people of the South, but we can make war so terrible and make them so sick of war that generations would pass away before they would again appeal to it.(McPherson, pg. 124) As stated in the article by Matt Carr, General Shermans March to the Sea, Shermans plan was to attack the infrastructure of the south and therefore end the war; After more than three years of violent and seemingly endless conflict, Sherman had decided to take the conflict beyond the battlefield and subject Georgia to a level of devastation that would make its population realise that w ar and ruin are synonymous terms. (pg. 30) Its hard to imagine that these strategies were those of a crazy man. Lincoln, the 16th president of the United States and the author of many documents most notably the Emancipation Proclamation was seen at least by one biographer, David Herbert Donald, to be passive. However, as stated in McPherson, at the very outset of his presidency Lincoln demonstrated traits that were the opposite of what Donald calls his essentially passive personality. (McPherson, pg. 207) Its hard to believe that the man that set into motion the Civil War and wrote one of our most historical documents has a passive personality. Maybe the passivity noted by some is more a compassion than anything else. As stated in, Lincolns Legacy, Lincoln Lives Through His Words by Gail Fineberg, Lincolns first draft of the Emancipation Proclamation, which he presented to his cabinet on July 22, 1862. Nobody liked it Sellers said. Lincoln came back to his cabinet with a second draft in September, and admonished members to comment not on substance but on his style. (pg 38) The quote goes witho ut saying to the mindset of a determined man more so to the mindset of a passive man. Although it may never be known the actual character of Grant, Sherman orà Lincoln, it will be left up to the readers and historians perceptions of whether are not these men were heroes, villains or maybe a little of both during and after the Civil War. It goes without saying that these men, however viewed, will always be remembered for the mark they left on the Civil War and wars to come. Polymerase Chain Reaction (PCR): Optimization Parameters Polymerase Chain Reaction (PCR): Optimization Parameters IGHODARO OGHOGHO UYIOSA Polymerase chain reaction (PCR): Evaluation of different optimization parameters for appropriate PCR process. Abstract PCR is a method used to produce relatively large amounts of a specific DNA sequence. The productivity of PCR method depends on different reaction conditions such as the concentration of the DNA template, concentration of magnesium ions, DNA template dilution and polymerase concentration. The aim of this study was to find optimal reaction conditions required for appropriate PCR process. To check the correct conditions the agarose gel and polyacrylamide gel electrophoresis were used. One single, strong amplified band and no unspecific product describe the most suitable amount of given conditions. In the results of this experiment, the most suitable annealing temperature was 62oC, the most proper amount of concentration of magnesium was 2nMol, and the best template dilution was 2à µl. The important parameters evaluated in this experiment were template optimisation, annealing temperatures and magnesium chloride concentrations with and without touchdown PCR. Introduction PCR is a simple, enzymatic assay, which allows for the amplification of a specific DNA fragment from a complex pool of DNA. PCR can be done using source DNA from a variety of tissues and organisms, including peripheral blood, skin, hair, saliva, and microbes. Only trace amounts of DNA are needed for PCR to generate enough copies to be analysed using conventional laboratory methods. For this reason, PCR is a sensitive assay (Lilit andNidhi 2013). To carry out a PCR it is essential to have the following reagents: DNA template, forward and reverse primers, PCR buffer, magnesium chloride (MgCl2), dNTP and DNA Taq polymerase. The annealing temperature allows for the annealing of the primers to the single stranded DNA. It depends on the length and composition of the primers. If the temperature is too high, then the primers will not anneal correctly, and if the annealing temperature is too low then the primers will anneal non-specifically (Hecker et al. 1996). Magnesium ions interact with the DNA polymerase enzyme during this process. The magnesium ion interacts with negatively charged molecules in the reaction. Positive ions of magnesium interact with the negatively charged DNA strands to mask the forces of repulsion (Markoulatos et al. 2002). Template DNA is a fragment of DNA which is needed to create required copies. DNA Taq polymerase is a polymerase enzyme, which is essential for DNA replication, this means that DNA polymerase synthesizes DNA molecules from their nucleotide building blocks (Huang et al. 1992). The nucleotides include the four bases ââ¬â adenine, thymine, cytosine, and guanine (A, T, C, G) ââ¬â that are found in DNA. These act as the building blocks that are used by the DNA polymerase to create the resultant PCR product. During this experiment, two methods were used to visualise the PCR products formed. These were Polyacrylamide gel electrophoresis (PAGE) and Agarose gel electrophoresis method. Electrophoresis is a separation procedure which is based on the separation of DNA fragments by size, shape and charge. The clue of this process is the mobility of ions in an electric field (nucleoid acids, which are negatively charged migrate to the anode ââ¬â positive electrode) (Stellwagen, 1998). Aim The aim of this experiment was to assess which parameters as annealing temperature, concentration of magnesium, and template DNA influence DNA amplification efficiency and specificity. 2.0à Materials and methods This section was divided into two parts. In part A, a PCR reaction 1 set-up using optimised PCR mastermix was done, while in part B, a PCR reaction was set-up to test four different variables to optimise a PCR reaction. 2.1à Part A Setting up the PCR reaction A mastermix enough for four reactions was made. 30à µl of H2O, 50à µl of 2X PCR mastermix and 4à µl each of forward and reverse primers were pipetted and mixed in an Eppendorf tube from which, 24à µl of the mastermix was pipetted into three separate PCR tubes (i.e. tube 1, 2, and 3). 1à µl of sample DNA, 1à µl of 1/10 diluted DNA and 1à µl of H2O were added to each tubes respectively and each amplified on a PCR block running the following programme: Denaturing step done at 94oC for two minutes Amplification step done at 94oC for 30 seconds, 55oC for 30 seconds and 72oC for 1 minute. This step was repeated for 35 cycles. Finally, the extension step was done at 72oC for 3 minutes. Agarose gel electrophoresis (2% agarose gel for PCR) An agarose gel was submerged in a gel tank filled with TBE buffer. Then 5à µl of gel loading buffer was added to each sample and mixed. Next, the first well was loaded with the molecular weight marker and then 10à µl of each sample was loaded into each respective wells. Next, the gel was run for 45 minutes at 80V. Finally, the gel was visualised on the gel documentation system to show separation and migration of the DNA. 2.2à Part B PCR optimisation reaction For this protocol, PCR reactions were set up and individual components of the reactions were varied in other to optimise them as follows: Annealing temperature optimisation 17.75à µl of water, 2.5à µl of 10x reaction buffer, 0.75à µl of Magnesium Chloride (50mMol), 0.5à µl of dNTPs, 1à µl each of forward and reverse primers, 0.5à µl of Taq polymerase and 1à µl of DNA were pipetted into 5 separate tubes (i.e. tube 1, 2, 3, 4, 5) which were then placed on a gradient PCR block, with one tube at each of the following temperature 46oC, 52oC, 55oC, 58oC, and 65oC. Next, the PCR block was set to the following programme: Denaturing step at 94oC for two minutes Amplification step at 94oC for thirty seconds, 46-65oC for thirty seconds, and 72oC for one minute. This stage was repeated for thirty-five cycles. Finally, the extension step was done at 72oC for three minutes. Template optimisation A PCR mastermix containing 13.75à µl of water, 2.5à µl of 10x reaction buffer, 0.75à µl of 50mMol magnesium chloride, 0.5à µl dNTPs, 1à µl each of forward and reverse primer and 0.5à µl of Taq polymerase were pipetted into five tubes. Next, 5, 2, 1, 0.1, and 0.01à µl of template DNA and, 0, 3, 4, 4.9. 4.99à µl of H2O were added to each tubes respectively. Next, the tubes were then amplified on a PCR block using the same cycle parameters as set out in part A. Magnesium concentration A PCR mastermix mastermix containing 16à µl of water, 2.5à µl of 10x reaction buffer, 0.5à µl dNTPs, 1à µl each of forward and reverse primer, 0.5à µl of Taq polymerase and 1à µl of DNA were pipetted into five tubes (i.e. tube 1, 2, 3, 4, and 5). Next, a Mgcl2 dilution was prepared to get a final Mgcl2 mMol of 0.5, 1.5, 2, 3 and 5mMol which were then added to each tubes respectively to give a final volume of 25à µl. Next, the tubes were then amplified on a PCR block using the same cycle parameters as set out in part A. Touchdown PCR A PCR mastermix was prepared using the same variables outlined for magnesium concentration. Then the touchdown PCR programme used was as follows: 94à °C for 3 minutes then 94à °C for 30 seconds, 64à °C for 30 seconds and 72à °C for one minute for three cycles, 94à °C for 30 seconds, 61à °C for 30 seconds, and 72à °C for one minute for three cycles, 94à °C for 30 seconds, 58à °C for 30 seconds, and 72à °C for one minute for three cycles, 94à °C for 30 seconds, 55à °C for 30 seconds, and 72à °C for one minute for three cycles, 94à °C for 30 seconds, 53à °C for 30 seconds, and 72à °C for one minute for thirty cycles, and finally 72à °C for three minutes. Sample preparation and polyacrylamide gel electrophoresis After all the different optimisation protocols, the samples to be loaded into the gel were prepared by adding 5à µl of loading buffer to each PCR reaction and mixed. Next, 5à µl of DNA ladder was pipetted into the first well while 10à µl of sample were pipetted into each designated wells. The gel was then run at 100V for 45 minutes. After which, the gel was recovered and placed in a weighing boat containing 1x TBE buffer. Next, 5à µl of ethidium bromide was carefully introduced into the weighing boat and left for 10 minutes before visualisation with a gel documentation system. 3.0à Result PCR reactions were set up in 5 different PCR tubes with all the required components for complete PCR reaction , save for a particular factor which was varied to ascertain the optimal concentration necessary for the production of the highest amount of pure specific product. The results obtained from these various optimised factors are represented in the gels below. Part A Optimized PCR 1à µl of DNA template was loaded in the well labelled neat DNA and it revealed the highest amount of product formed, the well containing a 1/10 diluted DNA had a much lower amount of product formed while the well with the water blank yielded no product. Also, unspecific products were not formed. Figure 1: Optimised PCR agarose gel. Part B The results of different PCR optimisation reactions PCR annealing temperature optimisation Figure 2: PCR annealing temperature optimisation polyacrylamide gel. Key: L-molecular weight ladder, lane 1- 48à °c, lane 2- 52à °c, lane 3- 55à °c, lane 4- 62à °c, lane 5- 65à °c, unspecific product, specific product. From Figure 2 above, there are three unspecific products formed in lane 1, a greater specific product with insignificant unspecific product formed in lane 2, insignificant unspecific products formed in lane 3 and there is also a decrease in the intensity of the specific product formed compared with that of lane 2. While in lane 4, there is a minor decrease in the intensity of the specific product formed thus, the intense quantity of the specific product formed (i.e. there is a strong amplification here) and in lane 5, there is a major decrease in the quantity of specific product formed. Therefore, the quantity of the product decreases as the quantity of the template DNA decreases, and the quantity of the specific and unspecific products increases as the quantity of the template DNA increase. Template dilution optimisation Figure 3: Template dilution optimisation polyacrylamide gel. Key: L -molecular weight ladder, lane 1- 5à µl, lane 2- 2à µl, lane 3- 1à µl, lane 4- 0.1à µl, lane 5- 0.01à µl template DNA, specific product, unspecific product. From the gel above, there are three unspecific products formed in lane 1 and also the intensity of the specific product formed is high, the unspecific product formed in lane 2 is insignificant and the specific product formed is greater in intensity (i.e. has a higher amplification) compared with that of lane 1, in lane 3 and 4, the intensity of the specific product formed decreased compared with that of lane 2, while in lane 5, there is a major decrease in the intensity of the specific product formed. Therefore, the quantity of the product decreases as the quantity of the template DNA decreases, and the quantity of the specific and unspecific products increases as the quantity of the template DNA increase. Magnesium dilution optimisation Figure 4: Magnesium dilution optimisation polyacrylamide gel. Key: L -molecular weight ladder, lane 1- 0.5mmol, lane 2- 1.5mmol, lane 3- 2mmol, lane 4- 3mmol, lane 5- 5mmol, specific product, unspecific product. Form the gel above, there is an unspecific and a specific product formed in lane 1, in lane 2 there is a decrease in the intensity of the unspecific product formed and also there is an increase in the amount of specific product formed. In lane 3, there were no production of unspecific products and the intensity of the specific product formed remained high. In lane 4, there is evidence of the presence of an unspecific product formed but the intensity of the specific product formed remained high. While in lane 5, there is a minor reduction in the intensity of the specific product formed while there is visible presence of formation of unspecific products. Magnesium touchdown optimisation Figure 5: ââ¬âTouchdown magnesium concentration optimisation. Key: L ââ¬â molecular weight ladder, lane 1- 0.5 mMol, lane 2- 1.5 mMol, lane 3- 2mMol, lane 4- 3 mMol, lane 5- 5mMol, unspecific product, specific product. From the gel above, in lane 1, the intensity of the unspecific product formed is the same with that of the specific product formed. While in lane 2, 3 and 4, the intensity of the specific products formed are the same while the intensity of the unspecific products gradually decreased. There was no unspecific product formed in lane 5, however there was a reduction in the intensity of the specific product formed compared to that of lane 4. Discussion This experiment was performed to evaluate different optimisation protocols to optimise PCR reactions. For the PCR reaction using an optimised PCR mastermix in part A, the highest amount of products formed was observed in the well containing 1à µl of DNA template.The annealing temperature is the most important optimisation, because it can have an influence on the specificity of the reaction. If the temperature is too high, the hybridization will not take place thus, templates and primers remain dissociated. If the temperature is too low, mismatched hybrids will occur. Correct annealing temperature must be low enough to start hybridization between template and primer, and also high enough to prevent forming mismatched hybrids (Roux, 2009). According to the results from annealing temperature optimization polyacrylamide gel (Figure 2), the most suitable annealing temperature was 62oC, because the band was clear and single as opposed to the 48oC, 52oC and 55oC, where the smears (i.e. unspecific products) were shown. The intensity of the band in 62oC was the strongest compared with that o f 65oC. The most suitable template dilution for PCR was 2à µl, because it gave in the polyacrylamide gel in Figure 3, the most bright, single band with very low amount of unspecific products formed. Besides, annealing temperature and template dilution parameters, PCR reaction components could also lead to non-specific amplification. Two variables, which are reported to greatly influence the specificity of the PCR reaction, are magnesium and dNTP concentration (Dwivedi et al. 2003). For magnesium dilution touchdown (Figure 5), the molarities at 1.5, 2 and 3mMol showed very similar amount of products formed indicating the importance of the magnesium in PCR amplification while for magnesium dilution without touchdown (Figure 4), it was found that 2mM yielded the best results. Magnesium concentration is known to play a critical role in amplification as it can affect DNA strand denaturation, primer annealing specificity and enzyme fidelity. These observations are in agreement with earlier studies (Innis et al. 1990; Eeles et al. 1993). Even brief incubations of a PCR mix at temperatures significantly below theTmcan result in primer-dimer formation and nonspecific priming. Hot-start PCR methods (Erlich et al. 1991;Ruano et al. 1992) can dramatically reduce these problems. In this experiment, two methods were used to visualise the PCR products formed. They are, Polyacrylamide gel electrophoresis (PAGE) and Agarose gel electrophoresis. Agarose gel is the most popular medium for the separation of moderate and large-sized nucleic acids and have a wide range of separation but a low resolving power, since the bands formed in the gels tend to be indistinct and spread apart. This is a result of pore size and cannot be largely controlled (Stellwagen, 1998). However, Polyacrylamide gels are normally more difficult to prepare and handle, and it requires a longer time for preparation than agarose gels. However, polyacrylamide gels have a greater resolving power, can accommodate larger quantities of DNA without any significant loss in resolution and the DNA obtained from polyacrylamide gels is extremely pure (Guilliatt, 2002). Hence, they are better than agarose gels. It should be noted that polyacrylamide is a neurotoxin (when unpolymerized), but with proper labo ratory care it is no more dangerous than various commonly used chemicals in the laboratory (Budowle Allen, 1991). Conclusion Optimisation of Polymerase Chain Reaction is very important for PCR performance to minimize failures, avoid the production of non-specific products and increase specificity of the reaction. The knowledge of proper conditions allows to use PCR correctly and to receive good results. According to the results of the research the most suitable annealing temperature was 62oC, the most proper amount of concentration of magnesium was 2nMol, and the best template dilution was 2à µl. Those parameters give DNA amplification specificity and efficiency. (Harris and Jones, 1997). References Alka, D., Sarin, B., Mittar, D., Sehajpal, P. (2003). OPTIMIZATION OF 38 kDa BASED PCR ASSAY FOR DETECTION OF MYCOBACTERIUM TUBERCULOSIS FROM CLINICAL SAMPLES. Journal of Tuberculosis. 50:209-213. Budowle, B. and Allen, R. (1991). Discontinuous polyacrylamide gel electrophoresis of DNA fragments. Methods in Molecular Biology. 9:123-132. Eeles, R. and Stamps, A. (1993). Managing the method. In Polymerase Chain Reaction (PCR) the Technique and its Application. Journal of Applied Sciences Research. 2(3): 12-26. Erlich,H.,Gelfand,D.,Sninsky,J. (1991).Recent advances in the polymerase chain reaction.Science.252:1643ââ¬â1651. Guilliat, A. (2002). Agarose and polyacrylamide gel electrophoresis: PCR mutation detection protocols. Methods in Molecular Biology. 187:125-137. Hecker,K. and Roux,K. (1996).High and low annealing temperatures increase both specificity and yield in touchdown and stepdown PCR.Bio Techniques. 20:478ââ¬â485. Harris, S. and Jones, D. (1997). Optimisation of the polymerase chain reaction. Journal of Biomedical Science. 54 (3):166-173. Huang, M., Arnheim, N., Goodman, M. (1992). Extension of base mispairs by Taq DNA polymerase: implications for single nucleotide discrimination in PCR.Nucleic Acids Research.20 (17):4567ââ¬â4573. Innis, M. and Gelfland, D. (1990). Optimization of PCRââ¬â¢s. In PCR protocols: A guide to methods and applications. Indian Journal of Tuberculosis. 118:1589-1599. Markoulatos, P., Siafakas, N., Moncany, M. (2002). Multiplex polymerase chain reaction: a practical approach.Journal of Clinical Laboratory Analysis.16(1): 47ââ¬â51. Lilit, G.andNidhi, A. (2013). Research Techniques Made Simple: Polymerase Chain Reaction (PCR). Journal of Investigative Dermatology. 133 (3): 4565-4579. Stellwagen, N. (1998). DNA gel electrophoresis. Nucleic Acid Electrophoresis Laboratory Manual. (D Tietz, Ed.). Springer Verlag. Berlin-Heidelberg-New York. Roux, K. (2009). Optimisation and troubleshooting in PCR. Cold Spring Harbour Protocols. doi:10.1101/pdb.ip66. Ruano,G.,Pagliaro,E., Schwartz,T.,Lamy,K.,Messina,D.,Gaensslen,R. et al. (1992).Heat-soaked PCR: An efficient method for DNA amplification with applications to forensic analysis.Bio Techniques.13:266ââ¬â274.
Wednesday, September 4, 2019
Funding Accommodation for NHS Service Users
Funding Accommodation for NHS Service Users The implications of providing and/or funding accommodation for service users under the NHS and Community Care Act 1990 and Mental Health Act 1983: Community care is wrought with conflicting duties, in the first instance carers in the community must preserve life and dignity but also fulfill the wishes of the client.[1] In respect to health and care management in the mentally ill there is various legal, moral and social implications for carers and the local authorities. The main question is whether the client should be moved from hospital to community care, because of their inability to care for themselves and the lack of services and accommodation.[2] In addition the reduction of costs on the state to have a fleet of 24/7 on calls aftercare services and the cost of providing individual housing[3]. Detention within a hospital unit is the biggest breach of human integrity, because the freedom of the individual has been taken away. In addition this may be the only avenue when the mentally infirm client refuses to take their medications and are unable to care for themselves and need 24/7 care, especially when there are no family me mbers able to care for them therefore leaving them as the responsibility of the state. It is a difficult position that carers are in, but extra resources and education sufficient care in the community is possible.[4] The following discussion is going to explore the duty that the local authorities hold to provide sufficient aftercare service, carers and housing to vulnerable persons once they have left the hospital scene. It will focus on the mentally ill, because there is a higher likelihood that housing and aftercare is needed for service users under section 117 of the Mental Health Act 1983 (MHA). Prior to this a discussion of detention and sectioning under the MHA will be discussed to illustrate that their human rights may easily be breached in the Local Authorities to provide sufficient aftercare, so that the individual may be further detained in the hospital facility. Under section 2 of the MHA an individual can be sectioned, which is detained for medical treatment on the grounds of mental illness, by an approved social worker or close family relative who is over 18. This means that the individualââ¬â¢s human right to liberty may be breached, therefore the law has to be certain that this right can be derogated in the circumstances. Under the 1983 Act the law requires that person sectioning the individual must have seen him in the last 14 days and this allows the individual to be detained for up to 28 days and the following admission procedure is adhered to: Two doctors must confirm that: (a) the patient is suffering from a mental disorder of a nature or degree that warrants detention in hospital for assessment (or assessment followed by medical treatment) for at least a limited period; and (b) she or he ought to be detained in the interests of her or his own health or safety, or with a view to the protection of others.[5] As a fail safe to incorrect detentions under section 2 of the MHA the individual can be released by the following individuals; RMO; hospital managers; the nearest relative, who must give 72 hours notice. The RMO can prevent her or him discharging a patient by making a report to the hospital managers. [Finally the] MHRT. [In addition] The patient can apply to a tribunal within the first 14 days of detention. [6] Therefore the law allows for the individual to be detained, but only if the person is honestly a threat to themselves and society, with mental illness it is highly that the person will be treated efficiently, but will need sufficient aftercare as mental health issues are usually long term. Under section 3 of the MHA it sets out the situation that the individual can be detained for; otherwise the individual should be given their liberty and given sufficient outpatient or aftercare service. Section 3(2) sets up three grounds that the individual can be detained for hospital treatment, which are: (a) he is suffering from mental illness, severe mental impairment, psychopathic disorder or mental impairment and his mental disorder is of a nature or degree which makes it appropriate for him to receive medical treatment in a hospital; and (b) in the case of psychopathic disorder or mental impairment, such treatment is likely to alleviate or prevent a deterioration of his condition; and (c) it is necessary for the health or safety of the patient or for the protection of other persons that he should receive such treatment and it cannot be provided unless he is detained under this section. All three grounds must be satisfied to detain the individual in hospital, otherwise there will be a breach of the individualââ¬â¢s right to liberty under the Human Rights Act 1998 (HRA). If hospital treatment is not warranted an application for guardianship for over 16ââ¬â¢s can be made either by the Local Authority or the person seeking guardianship; again as this threatens the integrity and the right to make oneââ¬â¢s own decisions that section 7(2) of the MHA states that the following two grounds must be complied with: (a) he is suffering from mental disorder, being mental illness, severe mental impairment, psychopathic disorder or mental impairment and his mental disorder is of a nature or degree which warrants his reception into guardianship under this section; and (b) it is necessary in the interests of the welfare of the patient or for the protection of, other persons that the patient should be so received. Therefore because the integrity of the individual is at threat and guardianship can include admission into hospital that the individual must be deemed as incapable for caring for themselves. The strict grounds stops the use of detention as a cheap option for Local Authorities over sufficient aftercare services; however an individual can get themselves admitted if they feel the need to be hospitalized for mental illness under section 131 of the MHA. In addition this act allows the individual to stop being discharged from the hospital, because the individual feels safe in the environment. As this is voluntary and the patient can decide to leave at any time this is not a breach of Article 5 of the European Convention on Human Rights (ECHR) as enacted through the HRA. Prior to moving on the provisions of Article 5 will be discussed as this is important to ensuring that the patient is discharged from forced detainment at the soonest possible moment and sufficient aftercare provided; other wise detainment could seen by the NHS and Local Authorities as a cost cutting measure to providing housing and aftercare services. Under Article 5(1)(e) it allows the detention of persons of unsound mind on the basis of lawful detention and procedure is prescribed under domestic law. The definition of unsound mind was left to an evolving definition in Winterwerp v Netherlands[7]; however detention can not be made merely on the basis that the individualââ¬â¢s belief system and behaviour are deviate from the norm. The use of detention under 5(1)(e) can only be for self-protection or the protection of the public, whereby the detention should only occur when; a medical disorder by an objective medical personnel; the nature and degree of the disorder is significantly extreme; and the detention is only as long as the medical disorder. In Ashingdane v UK[8] it was added that detention can only occur in a hospital or appropriate medical institution. The only circumstances that these requirements are weakened are with respect to emergency admissions but the detention should be properly assessed and continued detention should cease if the person is not of unsound mind[9]. Detention is an important part of mental health treatment and it is in these cases that treatment against oneââ¬â¢s wishes will occur. The state is required to provide an adequate level of medical treatment, including psychiatric care.[10] However, the patient should be released from detainment as soon as these grounds are no longer met as per section 16 of the MHA and sufficient aftercare service provided. This is an area of great concern when providing care in the area of the mentally infirm has always posed a difficult area for carers, doctors, nurses and human rights and consent is the key problem, because where does the law draw the line for treatment and incarceration into supervised care against or without the patientââ¬â¢s will? In most normal circumstances no treatment can be performed without the patientââ¬â¢s consent; however how does this work if the patient has been determined mentally incapable of making r ational decisions and therefore unable or unwilling to give consent. If a doctor has ordered that treatment should be made the question arises whether the nurse should still proceed, as it is in the best welfare of the patient or withhold treatment because the patient is unable or unwilling to give consent? Prior to the enactment of the HRA the problem of consent was a lot less murky as rights were given on the basis that there was no law restricting them, i.e. civil liberties. Therefore if parliament deemed that that rights such as consent for medical treatment should be restricted because of oneââ¬â¢s mental health this was justification enough, as parliament is supreme. The HRA changed this because a set of inherent rights were introduced which conflicted in cases with the will and supremacy of parliament, of which the right to a private life and the liberty and security of the person came to the forefront of the debate of consent and mental health, i.e. the person has the con trol to determine what happens to their body and freedom and this is not determined by the wishes, albeit good of parliament and using detainment as a cost effective measure and not providing a sufficient aftercare service is a breach of Article 5. In addition it breaches the statutory duty owed by the Local Authorities and the NHS under section 117 of the MHA and section 42 of the NHS and Community Care Act 1990 (NHSCCA). The following discussion is going to explore the duty to provide aftercare and consider whether it is being met, especially in the light of R v Ealing District Health Authority, ex parte Fox[11] where it was held under section 117 of the MHA: (1) that the authority has erred in law in not attempting with all reasonable expedition and diligence to make arrangements so as to enable the applicant to comply with the conditions imposed by the mental health review tribunal; (2) that a district health authority is under a duty under section 117 of the Mental Health Act 1983 to provide aftercare services when patient leaves hospital, and acts unlawfully in failing to seek to make practical arrangements for after-care prior to that patients discharge from hospital where such arrangements are required by mental health review tribunal in order to enable the patient to be conditionally discharged from hospital. Therefore the following discussion will explore these duties to provide sufficient aftercare services. In the case of the NHSCCA the case law and provisions are an amalgamation of a series of previous community care provisions, therefore these will be discussed and indicated to their standing within this act. Community care law and the provision of accommodation and after care services were provided as a statutory duty National Assistance Act 1948 (NAA). The NAA abolished the Poor Laws and imposed a duty on Local Authorities under section 21 to provide housing on those who by reason, illness, disability or any other circumstances are in need of care and attention which was not otherwise available to them. The NHSCCA amends section 21 to include nursing mother but upholds this duty to provide accommodation to the ill. This accommodation must be given to the individual free of charge or the Local Authority must pay for it, as they are unable to work under section 44-45 of the NHSCCA and section 117 of the MHA. As the cases of R v Manchester CC ex parte Stennet[12]; R v Redcar and Cleveland BC ex parte Armstrong[13]; and R v Harrow LBC ex parte Cobham[14] revealed that individuals that had been detained under section 3 and no longer fulfill these grounds must be provided sufficient aftercare services under section 117 of the MHA, sections 42-50 of the NHSCCA and the Health Act 1999 (HlthA) section 5 this soon not be provided at a cost to the individual. Under the NAA section 22 this charging regime did exist however this was repealed in the NHSCCA. In addition the Local Authority and Primary Care Trust it is also under a duty to provide services that are essential to the aftercare of the individual. Under section 29 of the NAA it was limited to only promoting other welfare arrangements, which included information, instruction and recreation in and outside their homes. The wording to promote welfare services was the downfall of the NAA because there was no obligation for the LA to provide these services, i.e. the LA has a discretion rather than a duty to provide such services.[15] However the Chronically Sick and Disabled Persons Act 1970 (CSDPA) where the Local Authority were obliged to provide services, including education and recreation; as well as sufficient adaptations to the home, access to holidays and meal provisions under section 2 of the CSPDA. This was confirmed in the case of R v Gloucestershire CC ex parte Barry[16]. Section 2 of the CSPDA has been called the finest community care statute[17] the disabled or chronic ally ill person under the act has a right to these resources regardless of whether the Local Authority has the availability of them, they must be provided upon request. This supports and strengthens the section 21 of the NAA, now section 42 of the NHSCCA[18] and section 2 of the CSPDA. However, the NHSCCA sections 46-50 and section 117 of the MHA have enforced the obligation to provide aftercare services after being released from hospital without charge[19]. This was confirmed in the case of Clunis v Camden and Islington HA[20]. In addition the Local Authority must provide payments or grants to ensure that the individual can live comfortably once released from the hospital, this is more applicable to physically disabled individuals and is confirmed under section 46-50 of the NHSCCA, for example section 47 determines the extent of aftercare services that the individual requires: (1)à Subject to subsections (5) and (6) below, where it appears to a local authority that any person for whom they may provide or arrange for the provision of community care services may be in need of any such services, the authorityââ¬â (a)à shall carry out an assessment of his needs for those services; and (b)à having regard to the results of that assessment, shall then decide whether his needs call for the provision by them of any such services. These services and the extent that they are provided are contained in a variety of acts, for example if the person requires adaptations to their home the Local Authority is under a duty to provide a grant if the individual cannot afford it. This right is protected under section 23 and 24 of the Housing Grants, Construction Regeneration Act 1996 (HGCRA). Section 23 and 24 imposes an obligation in the LA to make grants to make the necessary adaptations to their home, which is confirmed in the case of R v Birmingham CC ex parte Taj Mohammed[21]. If the individual needs to be housed in a special nursing home then the Local Authority is either entitled to provide the service or pay the registered nursing home for their services. This is protected under section 46 of the NHSCCA. This service should be provided efficiently and immediately and as with the Fox Case this should not be prolonged detention within a hospital. Section 50 of the NHSCCA provides the duty and guidelines for these pr ovisions and failure to do so will result in the investigation of the Local Authority. Section 50 of the NHSCCA has tried to deal with the problems with the current care framework, which is that although healthcare is free community care and carers provisions cost the individual who needs the aid. The individual has a right for community care to be provided, but in a lot of circumstances the receipt of funds to pay or the provision of the service can be delayed due to the Local Authorities and Primary Care Trusts fighting over who should foot the bill. This controversy has been risen in R (T) v Hackney[22] but has not been sufficiently resolved; rather the most appropriate authority must provide the care. Therefore section 50 (7)(e) states that: The Secretary of State may, with the approval of the Treasury, make grants out of money provided by Parliament towards any expenses of local authorities incurred in connection with the exercise of their social services functions in relation to persons suffering from mental illness. The problem with this is that it does not provide grants for the physically disabled, which means for these individualââ¬â¢s aftercare services will continue to be delayed to arguments over who will be paying the bill for the cost. In respect to housing this is the duty of the Local Authority and either housing should be directly provided or payment to a housing association or private landlord should be made. The other avenue that the Local Authority has is that the individual can receive direct payments for aftercare under the Community Care (Direct Payments) Act 1998 (CCDPA) renamed the Health and Social Care Act 2001 (HSCA). The individual with this money can pay their housing and choose an pay an appropriate carer and aftercare services. To be eligible the carer and aftercare service must be sufficiently educated to deal with the individualââ¬â¢s needs. In limited and exceptional circumstances a family member can be paid carers allowance, but it must be sufficiently illustr ated that this individual can meet the individualââ¬â¢s needs as per the Direct Payments Regulations 2003 Regulation 6. If the individual is unable to deal with their own care payments then the Local Authority must provide an agency that can deal with the aid of community care payments to be made to the carer. Under English law these agencies are called Independent User Trusts that provide the payments services for either the Local Authority or the Primary Care Trust, as supported by the cases of A v B v East Sussex.[23] This system means that the aftercare services and payments are NOT being directly paid therefore this leaves the possibility that the individual will use the money for other purposes and therefore the aftercare has to be provided at extra cost to the Local Authority, because there is a duty to provide under section 117 of the MHA sections 42-50 of the NHSCCA and section 5 of the HlthA. On the whole Local Authorities do not promote the use of Direct Payments becau se of the limitations of not aiding mental health service users and the extra expense of the Independent User Trusts. The Local Authority is under no duty to provide Direct Payments or information about then, just the services and care that are a duty; therefore the Local Authority is more likely to provide direct care services rather than payment. This is why in respect to housing the Local Authority is more likely to provide housing in housing trusts and make the payments directly to these entities, as council owned properties are less available. The duty to provide accommodation is also cemented in the Housing Act 1996 (HA), which has obligated special duties for Local Authority to provide housing in the rental sector for vulnerable adults, which includes those that come under section 117 of the MHA and sections 42-45 of the NHSCCA. There are still problems with effective community care, because as the Fox Case and the Stennet, Armstrong and Cobham Cases illustrated is that Local Authorities and Primary Care Trusts do not want to foot the bill for aftercare services. In the Fox Case continued hospitalization was argued for because it was cost effective, but as section 117 of the MHA states that if the individual is no longer detainable under section 3 and does not voluntarily remain under section 131 then release must occur. This duty to release and provision of sufficient community care is argued the best method for the mentally infirm and disabled.[24] Gitlin Cocoran[25] argue that the main health concerns are that of safety when dealing with dementia (as with other mental illnesses and the physically disabled) living at home alone or with family members and all that is needed are specific modifications to the physical environment to address these issues, and guiding principles for implementing environmental changes. This is provided under the NHSCCA, MHA and grants are available under the HGCRA, therefore there is no excuse that the individual cannot receive community care when hospitalization is not necessary. This has extra costs to the state, as the Fox Case illsustrates, in re-education and in cases of non-affordability of the adaptations; however it is usually easier and more cost-efficient to hospitalize the client but it is necessary so a breach of the clientââ¬â¢s human rights. Finally, studies such as Richards et al[26] and Schneider et al[27] argue that care of dementia is a much higher standard when within the community, because it reduces depression and gives a higher quality of life. As Barnett argues the individual should have a say in the caring strategy and forced hospitalization should only occur if section 3 of the MHA is fulfilled.[28] The law under the MHA, HlthA, NHSCCA and the HGCRA has made it a duty to the Local Authority that community resources should be ma de available therefore making hospitalization unreasonable and a breach of human rights[29]; however as the Fox Case has illustrated the Local Authorities will still attempt to dismiss this duty under the guise of necessary detention under the MHA or as with the Stennet, Armstrong and Cobham Cases charge the individual for their provision.[30] However, as these cases have enforced there is no charge and their provision is a duty at no charge and better cohesion between Primary Care Trusts and Local Authorities needs to occur to stop the passing of the bill from one agency to another, whilst the individual is either unfairly detained or without these essential services: Joint policies between PCTs/health authorities and social services are to be agreed to ensure the duty is met (HSC 2000/003). Where funding issues arise, and the health agencies are considering their obligation only to fund health costs under S.3 of the NHS Act 1977, regard may be had to the pooling arrangements for health and social care budgets under the Health Act 1999.[31] Bibliography: Alzheimers Disease Society, 1992, Safe as Houses Living alone with Dementia (A resource booklet to aid risk management) Alzheimerââ¬â¢s Disease Society London The Alzheimers Association, 2000, Guidelines for Dignity: Goals of Specialized Alzheimer/Dementia Care in Residential Settings, Alzheimerââ¬â¢s Association Chicago Antonangeli, 1995, Of Two Minds: A Guide to the Care of People with the Dual Diagnosis of Alzheimers Disease and Mental Retardation, Malden Barnett, 2000, Including the person with dementia in designing and delivering care: I need to be me! Jessica Kingsley Publishers Bowen, 2006, Human Rights Transforming Services, Social Care Institute for Excellence Brayne Carr, 2005, Law for Social Workers Oxford University Clements, 2004, Community Care and the Law London Legal Action Group (LAG) Cox, 1998, Home Solutions: Housing Support for People with Dementia, The Housing Associations Charitable Trust Day et al. 2000, The Therapeutic Design of Environments for People with Dementia: A Review of the Empirical Research, The Gerontologist 2000 (40) Day, 2002, The management of acute and chronic pain the community. Professional Nurse papers. 17(6) , Feb. 02. Department of Health, 2001, NHS Identity Guideline The Stationery Office Department of Health, 2004 Research Governance Framework Implementation Plan for Social Care DH ref 3402 Gitlin Cocoran, 2000, Making Homes Safer: Environmental Adaptations for People with Dementia Alzheimers Care Quarterly 1(1) Hoggett, 2002, The Family, Law and Society, LexisNexis UK Grubb, 2004, Principles of Medical Law 2nd Edition, Oxford University Press Hewitt, 2004, Between Necessity and Chance, NLJ 154(7124) Mahendra, 1998, Unto the Breach, The Practioner, in the NLJ 148(6857) Mind, Outline of the Mental Health Act 1983 http://www.mind.org.uk/Information/Legal/OGMHA.htm#s2 Mandelstan,1997, Equipment for Older or Disabled People and the Law Jessica Kingsley Mandelstan, 2005, Community Care Practice and the Law Jessica Kingsley McDonald, 1999, Understanding Community Care: A Guide for Social Workers Macmillan Meredith, 1995, The Community Care Handbook: The Reformed System Explained Age Concern NHS, Section 12(2) of MHA 1983 Website, can be found at: http://www.guideweb.org.uk/section12/section121.html Parsons, 2003, United Kingdom: Charging for Aftercare Services under s117 Mental Health Act 1983 ââ¬â The Final Story, RadcliffesLeBrasseur can be found at: http://www.mondaq.com/article.asp?articleid=22439print=1 Percy Commission, 1957 Report of the Royal Commission on the Law Relating to Mental Illness and Mental Deficiency Cmnd 169 1954-1957 Richards et al, 2000, Cognitive function in UK community dwelling African Caribbean and white elders: a pilot study International Journal of Geriatric Psychiatry 15 (7) Sandland Bartlett, 2003, Mental Health Law: Policy and Practice, Oxford Schneider et al,1997, Residential care for elderly people: an exploratory study of quality measurement Mental Health Research Review 4 WHO, 2003, Mental Health Legislation and Human Rights, WHO Footnotes [1] Keady, 2003 [2] Alzheimerââ¬â¢s Association Chicago, 2000 [3] Alzheimerââ¬â¢s Disease Association London, 1992 [4] Antonangeli, 1995 [5] Mind, Outline of the Mental Health Act 1983 http://www.mind.org.uk/Information/Legal/OGMHA.htm#s2 [6] Mind, Outline of the Mental Health Act 1983 http://www.mind.org.uk/Information/Legal/OGMHA.htm#s2 [7] (1979-80) 2 EHRR 387 [8] (1985) 7 EHRR 528 [9] Article 5(4) and Megyeri v Germany (1993) 15 EHRR 584 [10] The Greek Case [1969] 12 Yearbook 1 ; Cyprus v Turkey (1982) 4 EHRR 482; Keenan v UK [2001] The Times April 18th 2001 [11] [1993] 1 WLR 373 [12] [2002] 2 AC 1127 [13] [2002] 2 AC 1127 [14] [2002] 2 AC 1127 [15] Bowen, 2006 [16] [1997] AC 584 [17] Clements, 2005 [18] R v Kensington Chelsea RLBC ex parte Kujtim [1999] 2 CCLR 340 [19] R v Manchester CC ex parte Stennett [2002] unreported [20] [1998] 3 AER 180 [21] [1999] 1 WLR 33 [22] [2006] 9 CCLR 58 [23] [2003] CCLR 177 [24] Day et al, 2000 [25] Gitlin Cocoran, 2000, pgs. 50-58 [26] Richards et al, 2000 [27] Schneider et al, 1997 [28] Barnett, 2000 [29] Cox, 1998 [30] Parsons, 2003 [31] Parsons, 2003
Tuesday, September 3, 2019
Five Senese Aging Essay -- essays research papers
à à à à à ââ¬Å"Aging is a process of one getting older...â⬠(Medina 4). As one gets older changes will occur. ââ¬Å"It might start with a line a cross the forehead that deepens in to a wrinkle or skin that suddenly appears dull lookingâ⬠(Tomas E1). No mater what the situation aging has many different processes. This literary composition will show the different changes that the senses go through when aging takes place. à à à à à Seeing is one of the senses humans have. Although humans really see with their brains the eyes are the key tools that help the task of seeing. Unlike other parts of the body nearly every part of the visual system is affected by aging. It causes us to lose certain functions as we age like loss of color to how the way we see near and distant objects. ââ¬Å"The cornea, that fluid-filled bad which guards the entrance to the eye, ages as we get older...by the time we get to the age of 60, the bag brings to flatten, which alters our visual fieldâ⬠(Medina 189). Perhaps the most interesting aspect of our vision systemââ¬â¢s aging has to do with color perception. As we get older the lens not only thickens but also takes on a yellowish color. This reduces our ability to discriminate between colors. à à à à à Hearing is also one of our senses and as we get older the ability of hearing gets weak. Once we age the pinna, the outer ear, losses some flexibility. As a result it begins to droop, becomes longer and wider and m...
The U.S. Involvement in the Vietnam War Was Justified Essay example --
The U.S. Involvement in the Vietnam War Was Justified à à à à à The Vietnam conflict has been known for being the most unpopular war in the history of the United States. The war of 1812, the Mexican war and the Korean conflict of the early 1950's were also opposed by large groups of the American people, but none of them generated the emotional anxiety and utter hatred that spawned Vietnam. The Vietnam war caused people to ask the question of sending our young people to die in places where they were particular wanted and for people who did not seem especial grateful. à à à à à Vietnam has a very rich and cultural diverse background dating all the way back to 1066 when William the Conqueror invaded and paved the way for English colonization. The French had been colonizing since the 19th century. The French role in Vietnams history is critical; they started out by bringing these simple peasants to the latest technology of farming and hunting (Yancey 37). The French helped these people out greatly in the beginning, but like all stories of occupation go they just got worse. They started forcing rules and laws on the people of Vietnam. Thus started the First Vietnam War, also known as the Indochina War between France and Vietnam. "The French possessed military superiority, but the Vietnamese had already the hearts and minds of the country. (38). Even from the beginning the Vietnamese had the odds to there favor. The French looked at the wars in numbers and how many lost on each side. They gathered from all the battles that they were winning because the Vietnamese casualties far outweighed the French; nonetheless they were wrong. To a certain point the French were fighting a game that they could not win at any cost. The French had the military superiority but the Vietnamese had the manpower and the Guerilla tactics. The Indochina War ended with French loosing terrible at Dienbienphu, where a whole French garrison was wiped out. à à à à à When Vietnamese revolutionary Ho Chi Minh and his political organization, the Vietminh, seized control of their independence from France United States Politicians saw it as another communist take over. When really Ho was more a nationalist than a communist. All Minh wanted was for the United States to recognize its independence from France and to send aid to help it reach its nationalistic goals. "Before the Cold War Ho and the Vietmin... ... of South Vietnam that resulted in the fall of Saigon on 30 April. In the previous month a RAAF detachment of 8 Hercules transports flew humanitarian missions to aid civilian refugees displaced by the fighting, and carried out the evacuation of Vietnamese orphans before finally taking out embassy staff on 25 April (Dudley 179). The US did the same exact thing except there were many people left behind that we could not transport due to the importance of emptying out embassy. Over fifty countries pooled resources together but out of all the United States had a much bigger sacrifice, the ultimate sacrifice, the sacrifice of our young men. These men started coming into Vietnam as early as 1962.à à à à à à à à à à The Vietnam War was a very mismanaged war but our involvement was very crucial. Some people believe that the side we were on was wrong, and the author of this completely agrees. Ho Chi Minh was really a quite conservative communist leader. He was fair and he was also was balanced. He treated his people very fairly. The beliefs of the author are that if Truman would have not set the precedent of opposing all communist leaders than the Vietnam War would have been a lot different. The U.S. Involvement in the Vietnam War Was Justified Essay example -- The U.S. Involvement in the Vietnam War Was Justified à à à à à The Vietnam conflict has been known for being the most unpopular war in the history of the United States. The war of 1812, the Mexican war and the Korean conflict of the early 1950's were also opposed by large groups of the American people, but none of them generated the emotional anxiety and utter hatred that spawned Vietnam. The Vietnam war caused people to ask the question of sending our young people to die in places where they were particular wanted and for people who did not seem especial grateful. à à à à à Vietnam has a very rich and cultural diverse background dating all the way back to 1066 when William the Conqueror invaded and paved the way for English colonization. The French had been colonizing since the 19th century. The French role in Vietnams history is critical; they started out by bringing these simple peasants to the latest technology of farming and hunting (Yancey 37). The French helped these people out greatly in the beginning, but like all stories of occupation go they just got worse. They started forcing rules and laws on the people of Vietnam. Thus started the First Vietnam War, also known as the Indochina War between France and Vietnam. "The French possessed military superiority, but the Vietnamese had already the hearts and minds of the country. (38). Even from the beginning the Vietnamese had the odds to there favor. The French looked at the wars in numbers and how many lost on each side. They gathered from all the battles that they were winning because the Vietnamese casualties far outweighed the French; nonetheless they were wrong. To a certain point the French were fighting a game that they could not win at any cost. The French had the military superiority but the Vietnamese had the manpower and the Guerilla tactics. The Indochina War ended with French loosing terrible at Dienbienphu, where a whole French garrison was wiped out. à à à à à When Vietnamese revolutionary Ho Chi Minh and his political organization, the Vietminh, seized control of their independence from France United States Politicians saw it as another communist take over. When really Ho was more a nationalist than a communist. All Minh wanted was for the United States to recognize its independence from France and to send aid to help it reach its nationalistic goals. "Before the Cold War Ho and the Vietmin... ... of South Vietnam that resulted in the fall of Saigon on 30 April. In the previous month a RAAF detachment of 8 Hercules transports flew humanitarian missions to aid civilian refugees displaced by the fighting, and carried out the evacuation of Vietnamese orphans before finally taking out embassy staff on 25 April (Dudley 179). The US did the same exact thing except there were many people left behind that we could not transport due to the importance of emptying out embassy. Over fifty countries pooled resources together but out of all the United States had a much bigger sacrifice, the ultimate sacrifice, the sacrifice of our young men. These men started coming into Vietnam as early as 1962.à à à à à à à à à à The Vietnam War was a very mismanaged war but our involvement was very crucial. Some people believe that the side we were on was wrong, and the author of this completely agrees. Ho Chi Minh was really a quite conservative communist leader. He was fair and he was also was balanced. He treated his people very fairly. The beliefs of the author are that if Truman would have not set the precedent of opposing all communist leaders than the Vietnam War would have been a lot different.
Monday, September 2, 2019
Famous Immigrant Entrepreneur from Pakistan in USA Essay
Edible Arrangements is a U. S. -based franchising business that specializes in fresh fruit arrangements, melding the concept of fruit baskets with design inspired by the floral business The company is headed by Tariq Farid, who partnered with his brothers to open the first Edible Arrangements store in Hamden, Connecticut in 1999. After designing the computer systems, training manuals, production and profitability tracking and supply chain management process, they began franchising the concept in 2001. As of 2008, the business had grown to more than 900 stores serving locations in the United States, Canada, Puerto Rico, the United Arab Emirates, Saudi Arabia and the United Kingdom. In March 2008 Edible Arrangements was reported to have annual revenues of $195 million Netsolace Netsolace is a technology company that provides groundbreaking technology solutions for the franchise industry. For franchisors seeking the ultimate control over their businesses, both in terms of relationship management and operational efficiency, Netsolace offers a suite of proven software solutions that enables better monitoring, communications and data management at each stage of the franchise lifecycle. Our comprehensive suite of convenient and flexible web-based applications can be accessed from anywhere. They are designed to support both the franchisor and franchisee business needs and provide real time information for comprehensive data analysis and management reporting. To see how we can help you, please review our site or contact us. We will be happy to answer your questions and demonstrate how our solutions can help your business and its bottom line. Life History Tariq Farid was born near Lahore, Pakistan, in 1969, the oldest of six children of Glulam and Salma Farid. His father immigrated to the United States in the 1970s, working in Connecticut as a machinist. Tariq Farid arrived in the United States with the rest of the family in 1981, when he was 11 years old. As a teenager, Tariq mowed lawns and worked in a McDonaldââ¬â¢s restaurant. In 1986, when he was 17, the family bought and began operating a flower shop in East Haven, Connecticut. While working in the family business, which expanded to additional locations, Tariq developed a computerized point of sale system for floral shops, and struck out on his own in 1991 in a business selling computer systems to flower retailers. Tariq launched the first Edible Arrangementsà ® store in 1999 in East Haven, Connecticut. He was inspired by the convergence of three trends: Americansââ¬â¢ growing consumption of fresh fruit, the robust growth in the specialty food market and the increasing amount of money Americans were spending on gifts. Edible Arrangementsà ® was named one of Americaââ¬â¢s fastest-growing privately held businesses in America by Inc. magazine and one of the top franchise systems in Entrepreneur Magazineââ¬â¢s Franchise 500. Tariq has four pending U. S. patents for proprietary fruit-cutting equipment that he designed. Achievements In 2009 Tariq was recognized as Entrepreneur of the Year by the International Franchise Association. IN 2009 Tariq was named the Ernst & Young Entrepreneur of the Year. He spoke at the 3rd Leadership Summit held by the council for the advancement of Muslim Professionals and at the Small Business Summit held by The New York Times. Tariq Farid was born in Pakistan in 1969 and immigrated to the United States at age 11. He grew up in West Haven, Connecticut and became a U. S. citizen in 1986. He developed the Salma K Farid Academy, a non-profit learning and community center, to honor the wishes of his late mother whom he credits as the inspiration for his success, and the Salma K Farid Foundation to provide for those in need Current Capital 700 Million Dollars His Interview Published in New York Time I WAS born in Pakistan and came to the United States in 1981, when I was 11. My grandfather owned a farm in Pakistan and we had been fairly well-to-do. We started at the bottom when we came here. My father found a job as a machinist during the day and worked at McDonaldââ¬â¢s and Burger King at night. All five of my siblings pitched in. I delivered newspapers to 300 houses. Instead of putting the paper into the mailbox, Iââ¬â¢d deliver it to the door. I got great tips. When I was 13, a flower shop hired me to water the flowers. Soon I was taking care of orders. By 16, I had learned a lot. One day my father found a flower shop for sale in the paper. The owner wanted $6,000. My dad asked me if I could run the shop, and I said sure. We got a cash advance and a loan from a friend. I thought Iââ¬â¢d negotiate, and asked the owner what terms he was offering. He looked at me as if to say, ââ¬Å"What can this kid possibly know? â⬠We opened a week before Easter and earned about $50 a day. I stayed open until 7 p. m. , seven days a week, because few other flower shops did. I thought $350 a week was wonderful. Soon, sales doubled, and I was shocked. Five years later, we had three shops and were making close to $1 million a year. I said we needed to make more, about $5,000 a day. My mother asked me if I remembered when I was making $50 a day and she suggested that I relax. I told her that it never really ends, and that I could achieve that goal. It was a lot of work. I didnââ¬â¢t really have a social life. We stayed open on holidays. On my way to high school, Iââ¬â¢d drop off my mother at the shop. She spoke no English, so I told her what to do to supervise the two employees. After school Iââ¬â¢d make flower arrangements and deliver them myself until I could hire a driver. I attended college part-time, but I started weighing the benefit against what I was making. I decided to put off school, and I never finished. I was so young when I started a career that I blindly jumped into it. Edible Arrangements, which I started in 1999 with my brother, Kamran, goes back to our roots. In Pakistan, my father always brought home tons of fruit for us. When we started the company, we created basic fruit arrangements that included fresh pineapple, strawberries, cantaloupe and more, and later added extras like chocolate and cinnamon toppings. We got 30 orders the first day. We had learned from our flower stores, so this time did everything right. A stranger asked about opening a store, which gave us the idea to franchise them. I knew nothing about the franchise industry, so I contacted an association for the names of experts and found Michael Seid. He gave great advice. Iââ¬â¢ve started several other companies. One is Frutation by Edible Arrangements, which includes salads and fruit drinks. Theyââ¬â¢re sold in Edible Arrangements stores and stand-alone stores. I also started Netsolace, which provides software for the franchise industry. Another, Berry Direct, offers containers, vases and other products to our Edible Arrangements franchisees and other companies. I just started the Farid Capital Corporation; a financing company that helps franchisees buy equipment. When I was starting out, I used to give my mother $50 a week. When I wanted to buy a building for our second Edible Arrangements location, I needed $40,000 more than I had. My mother had saved the money I gave her over the years and handed it back to me. She asked only that I do something in her name someday and give her $20,000 for my sisterââ¬â¢s wedding. When my mother passed away in 2000, I started a foundation in her memory. The organization built a hospital in Pakistan for needy people and an Islamic school in the United States.
Sunday, September 1, 2019
Different Aspects of Emily Essay
Often people are stuck in the past and cannot accept the truth, the present, and modernization going around them. The character of Emily Grierson in William Faulknerââ¬â¢s ââ¬Å"A Rose for Emilyâ⬠is one from this category of people. Emily Grierson was a strange personality with distinguished characteristics. From the point of view of many, she is a crazy woman because she kills her lover in order to keep him forever with herself. Miss Emily Grierson is a static character that is locked in her past life. She is not able to change herself and roll on with the wheels of time. William Faulkner, through the use of various symbols indicating death and decay, portrayed a woman whose life ends long before her death. The first and one of the significant symbols of death and decay presented in the story is Miss Emilyââ¬â¢s house itself. The look, setting and atmosphere of the house provide us with the features of death and decay in Emilyââ¬â¢s life. The street where her house is located has changed completely except Miss Emilyââ¬â¢s house. ââ¬Å"Garages and cotton gins had encroached and obliterated even the august names of that neighborhoodâ⬠(28). The house that once had been beautiful is destroyed now. ââ¬Å"â⬠¦lifting its stubborn and coquettish decay above the cotton wagons and the gasoline pumps- an eyesore among eyesoresâ⬠(28). Cotton gins, cotton wagons, and the gasoline pipes are all symbols indicating the new and modernized era and period where still stands, Emilyââ¬â¢s old and destroyed house. Emilyââ¬â¢s house was an eyesore in the city, and Emily herself was a greater eyesore in her society. The entire look from the inside of the house is also a symbol representing death and decay. The inside of her house is explored in the story for the first time when the deputation committee came to ask Miss Emily to pay her taxes. They passed through the door that no visitor had passed since a long time and entered a dim hall. ââ¬Å"When the Negro opened the blinds of one window, they could see that the leather was cracked; and when they sat down, a faint dust rose sluggishly about their thighs, spinning with slow motes in the single sun-rayâ⬠(29). The old furniture in her house, the cracks on her sofa and the dust-covered things in the place suggest the dark aspect of herà life. The darkness and dimmed atmosphere of the place, throw us into an aura of dullness and sadness that demonstrates the significant feature of Emilyââ¬â¢s character. Miss Emily Grierson, herself is the most important symbol representing death and decay in her own life. Her appearance, face and her features all suggest a sort of dullness and stillness in her life. ââ¬Å"She looked bloated, like a body long submerged in motionless water, and of that pallid hue. Her eyes, lost in the fatty ridges of her face, looked like two small pieces of coal pressed into a lump of dough as they moved from one face to anotherâ⬠¦Ã¢â¬ (29). The description of Emily and the features of her face provided by the author demonstrate the dry and deadly character of Emily more clearly. Miss Emily is also a very unsocial and isolated person. The over protecting behavior of her father and too many restrictions put upon her by him, had a great influence and impact in shaping her personality. She lacks the elements of active social life and art of communication in her life. Emily has an extremely proud and self-important disposition because of her family status. ââ¬Å"She carried her head high enough- even when we believed that she was fallenâ⬠(32). This sentence portrays her aristocratic behavior and high attitude. Her aristocratic behavior isolates her more from the society, leaving her alone with her gradual death, her sole companion. Emilyââ¬â¢s inability to accept the present and change itself is a significant symbol demonstrating death and decay in her life. For example, when authorities come to her and ask her to pay her taxes she in return tells them; ââ¬Å"See Colonel Sartoris. I have no taxes in Jeffersonâ⬠(30). At that time, nearly ten years had passed since the death of colonel Sartoris. This instance clearly shows Emilyââ¬â¢s involvement in her past life, and the fact that she was not moving on with the pace of time. Another scene more clearly depicting this characteristic of Emily is when her father dies; she keeps the dead body of her father for three days in her house. After the death of her father she cuts her hair short; ââ¬Å"â⬠¦her hair was short, making her look like a girlâ⬠¦Ã¢â¬ (31). This incident also emphasizes that she wants to be her fatherââ¬â¢s little daughter again. This incident demonstrates that she does not have the ability to accept the reality, or maybe she does not want to do so. Homer Barron is a symbol representing modernization and arrival of new period and age. Homer is a Northerner, a Yankee, presenting the era of manufacturing industry, technology, innovation, and reconstruction. His purpose of coming to the South is to work for construction and renovation; paving the sidewalks of the city. His personal character also demonstrates elements of modernization. He does not care about the code of behavior which is important in Emilyââ¬â¢s community, a Southern society. The story presents Homer as a person who is not a marrying man and likes to be free and prefers bachelor life. ââ¬Å"Whenever you heard a lot of laughing anywhere about the square, Homer Barron would be in the center of the groupâ⬠(31). The description of Homer Barron in the story suggests that he was a carefree person, liked parties and enjoyed meeting with others. It also demonstrates his lively character which is completely the opposite personality of Emily Grierson. Homer was a person representing present and future, and Emily can not leave her past and move ahead so she kills Homer and keep him for ever hers. All of the symbols present the isolated and steady character of Emily, which was still and static through the passage of time. Emilyââ¬â¢s soul was covered with the dust of loneliness and dimmed by grief, sorrow and everlasting sadness. In the story ââ¬Å"fallen monumentâ⬠refers to Emily. Emily was a monument, a legend that has been ruined and shattered by the passage of time because of lack of care and attention. Not a single light of joy or happiness was in her life. Being a young woman, once she had been beautiful and attractive, but she was left alone because of the circumstances in her life. Emily lost her soul gradually through her lifetime and was actually dead long before her death. Work Cited Faulkner, William. ââ¬Å"A Rose for Emily.â⬠Literature: An Introduction to Fiction, Poetry, and Drama. Ed. X. J. Kennedy and Dana Gioia. 8th ed. New York: Longman, 2002. 28-35.
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